Those with metabolic/mitochondrial disorders and those with certain genetic mutations have been determined to be at greater risk of vaccine injury. Metabolic/Mitochondrial Disorders Learn How to Recognize the Signs and Symptoms of Vaccine Reactions 69 Doses of 16 Vaccines by Age 18? Before you take the risk, find out what it is. VACCINE CONTRAINDICATIONS: SIX PEOPLE WHO SHOULD NOT BE VACCINATED Vaccinations are not right for everyone. There are at least six types of people in particular who should avoid vaccinations, and below, I’ll spell it out.